Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length185 amino acids

Chemical FormulaC922H1442N252O251S7

DescriptionStandard

        PMALPTAHEPMVLLAITEFVANSAAFTYFSAGALRRNISGNTLPRHFPLQLKTKSTEIFAPQLQEQYPDQPMELLLWARQQPLLSCRPDALHGTLFGSAEAFVVLPNATRVPVFLLNIDANVTGKPTLSGNRLGASPQWGAQPWPCQAHVSPRPQVQKLETLLKLGLRLFGVPWANSECCPRPAP
    

Molecular Weight20297.31 Da

Isoelectric Point (pI)9.13

Net Charge (pH 7.0)4.29

Net Charge (pH 7.4) 3.94

Charge Density (pH 7.0) 0.0232

GRAVY Index-0.06

Hydrophobic Moment 0.65

Boman Index0.11

Instability Index50.54

Aliphatic Index 89.73

Aromaticity 0.0811

Extinction Coeff. Reduced 24980.00

Extinction Coeff. Oxidized 25230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7883.51

LogP -89.29

H-bond Donors 266.0

H-bond Acceptors 266.0

Rotatable Bonds 632.0

Heavy Atoms 1432.0

Ring Count 45.0

Amide Bonds 204.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0180358 VERIFIED: NO

Provenance & Taxonomy

OrganismPiaya cayana [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria