Peptide Database

Peptide NameOncostatin-M

Function Ontology

Immunology ▸ Immune modulation ▸ Cytokine modulation

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Standard StatusStandard

Sequence Length196 amino acids

Chemical FormulaC960H1558N300O285S9

DescriptionStandard

        AAIGSCSKEYRVLLGQLQKQTDLMQDTSRLLDPYIRIQGLDVPKLREHCRERPGAFPSEETLRGLGRRGFLQTLNATLGCVLHRLADLEQRLPKAQDLERSGLNIEDLEKLQMARPNILGLRNNIYCMAQLLDNSDTAEPTKAGRGASQPPTPTPASDAFQRKLEGCRFLHGYHRFMHSVGRVFSKWGESPNRSRR
    

Molecular Weight22151.06 Da

Isoelectric Point (pI)9.54

Net Charge (pH 7.0)8.21

Net Charge (pH 7.4) 7.66

Charge Density (pH 7.0) 0.0419

GRAVY Index-0.64

Hydrophobic Moment 0.81

Boman Index-0.17

Instability Index60.96

Aliphatic Index 79.69

Aromaticity 0.0561

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11710.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 9506.55

LogP -124.92

H-bond Donors 336.0

H-bond Acceptors 307.0

Rotatable Bonds 710.0

Heavy Atoms 1554.0

Ring Count 29.0

Amide Bonds 214.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0143802 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyLIF/OSM family

Tax ID9606; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide6-127; 49-167

Bio-Activity Profile

Function

Cytokine Growth factor LIF OSM family Growth factor signaling