MYP_070478
Rezafungin
Antimicrobial
Antimicrobial
▸
Antifungal
Antimicrobial
▸
Antifungal
▸
Anti-Aspergillus
Antimicrobial
▸
Antifungal
▸
Anti-Candida
not Standard
7 amino acids
-
contains X representing unresolved or non-standard residue
XXTXXTX
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Amino Acid Composition
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0209976
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Echinocandin
32630
Structure & Mods
side-chain cyclized peptide [Cyclic]
noncanonical stereochemical modification [Modified]
4''-(pentyloxy)-[1,1':4',1''-terphenyl]-4-carboxamide
Macrocyclized C-terminus
Non-standard residues/X at 1, 2, 4, 5, 7; Lipidation (4''-(pentyloxy)-[1,1':4',1''-terphenyl]-4-carboxamide)
Bio-Activity Profile
Antimicrobial
Antifungal
Anti-Candida
Anti-Aspergillus
Fungal β-1, 3-D-glucan synthase
Clinical/Human: 152 h.
RECORD: Rec_0274217
VERIFIED: YES
Provenance & Taxonomy
Aspergillus nidulans [Fungus]; synthetic construct [Synthetic]
Echinocandin
32630
Structure & Mods
side-chain cyclized peptide [Cyclic]
noncanonical stereochemical modification [Modified]
Benzoyl
Macrocyclized C-terminus
Non-standard residues/X at 1, 2, 4, 5, 7
Bio-Activity Profile
Antimicrobial
Antifungal
Anti-Candida
Anti-Aspergillus
Fungal β-1, 3-D-glucan synthase
Clinical/Human: 40-50 h