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MYP_070470
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Basic Information
Beta-defensin
Antimicrobial
Antimicrobial ▸ Antibiotic activity
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
93 amino acids
C479H773N143O132S10
Standard
Sequence
MKFFLFFVILLAMEPVISEECWMNGKCRLVCKSDEDSVVRCENRKRCCVPSRYLTVQPMTVERIEPETVPHTPKPVKHKHRPDSKQNRNVHGR
Physicochemical Analysis
10967.79 Da
9.21
5.81
5.27
0.0624
-0.56
0.51
-0.18
61.67
68.92
0.0645
6990.00
7365.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
4437.11
-40.72
159.0
152.0
363.0
764.0
19.0
98.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0372506 VERIFIED: NO
Provenance & Taxonomy
Canis lupus dingo [Animal]
Defensin
Structure & Mods
disulfide-stabilized linear peptide scaffold [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Defensin
Evidence URLhttps://www.uniprot.org/uniprotkb/A0A8C0JU80/entry
RECORD: Rec_0414737 VERIFIED: NO
Provenance & Taxonomy
Canis lupus familiaris [Animal]
Defensin
9615
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal
Qualitative functional evidence
PaperCross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract PMID16033865 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16033865/; https://www.uniprot.org/uniprotkb/Q30KT4/entry; https://bblserver.org.in/ampdb/