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MYP_070435
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Basic Information
Myeloid antimicrobial peptide BMAP-27(1-18)-L, BMAP-18-L
Antimicrobial
Antimicrobial ▸ Antibacterial
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
18 amino acids
C101H196N34O20
Standard
Sequence
GRLKRLRKKLKKLLKKLS
Physicochemical Analysis
2206.85 Da
12.00
9.75
9.54
0.5418
-1.07
0.79
-0.64
9.96
130.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
946.09
-5.77
36.0
30.0
88.0
155.0
0.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0348625 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Salmonella typhimurium KCTC 1926
2 μM
MIC
PMID21497177 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21497177/
RECORD: Rec_0380345 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 83.3%, E 0.0%, T 5.6%, C 11.1% [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Toxic Antimicrobial Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0380364 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-inflammatory
Staphylococcus aureus MRSA
16 μM
MIC
PaperMultifunctional Properties of BMAP-18 and Its Aliphatic Analog against Drug-Resistant Bacteria.
RECORD: Rec_0412214 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Human erythrocytes
300 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/21497177/ PMID21497177 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21497177/
RECORD: Rec_0421756 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Bacillus subtilis KCTC 3068
4 μM
MIC
PMID21497177 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21497177/
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