Peptide Database

Peptide NameCycloviolacin H2

Function Ontology

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Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC123H195N31O38S6

DescriptionStandard

        SIPCGESCVWIPCITAIAGCSCSNKVCY
    

Molecular Weight2908.44 Da

Isoelectric Point (pI)5.71

Net Charge (pH 7.0)-0.60

Net Charge (pH 7.4) -0.90

Charge Density (pH 7.0) -0.0214

GRAVY Index0.86

Hydrophobic Moment 0.24

Boman Index0.33

Instability Index32.40

Aliphatic Index 83.57

Aromaticity 0.0714

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1075.02

LogP -12.23

H-bond Donors 43.0

H-bond Acceptors 44.0

Rotatable Bonds 87.0

Heavy Atoms 198.0

Ring Count 5.0

Amide Bonds 28.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0264204 VERIFIED: YES

Provenance & Taxonomy

OrganismOldenlandia affinis [Plant]

FamilyCyclotide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)