Peptide Database

Peptide NameDefensin beta 1 (beta-defensin 1)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length69 amino acids

Chemical FormulaC343H541N101O94S9

DescriptionStandard

        MKTHYFLLVMLFFLFSQMEPGAGILTSLGRRTDQYRCLQHGGFCLRSSCPSHTRLQGTCKPDKPNCCRS
    

Molecular Weight7872.17 Da

Isoelectric Point (pI)9.34

Net Charge (pH 7.0)5.70

Net Charge (pH 7.4) 5.24

Charge Density (pH 7.0) 0.0826

GRAVY Index-0.24

Hydrophobic Moment 0.56

Boman Index-0.04

Instability Index63.59

Aliphatic Index 62.17

Aromaticity 0.1014

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3132.80

LogP -33.26

H-bond Donors 117.0

H-bond Acceptors 112.0

Rotatable Bonds 257.0

Heavy Atoms 547.0

Ring Count 14.0

Amide Bonds 73.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0156680 VERIFIED: NO

Provenance & Taxonomy

OrganismPeromyscus maniculatus bairdii [Animal]

FamilyDefensin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Non-hemolytic Non-ribosomal