MYP_070422
Basic Information
Crotalicidin
Anticancer
Anticancer Cytotoxic anticancer activity Cytotoxic
Antimicrobial
Antimicrobial Antibacterial
Antimicrobial Antibacterial Anti-Gram-negative
Antimicrobial Antibacterial Anti-Gram-positive
Antimicrobial Antifungal
Immunology Innate immune defense Host defense peptide Host defense activity
Toxicity / Safety Blood cell toxicity Hemolysis Hemolytic
Toxicity / Safety Cytotoxicity Cytotoxic
Venom / Toxin General toxin Cytotoxic
Standard
34 amino acids
C203H345N53O37S
Standard
Sequence
KRFKKFFKKVKKSVKKRLKKIFKKPMVIGVTIPF
Physicochemical Analysis
4152.31 Da
12.00
14.75
14.52
0.4337
-0.44
0.82
-0.23
4.32
80.00
0.1471
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1508.56
-4.61
54.0
53.0
152.0
294.0
7.0
33.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0412079 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on American pit vipers [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
C. tropicalis LABMIC 0109
10-40 μM
MIC
Serum 71 min
RECORD: Rec_0414133 VERIFIED: YES
Provenance & Taxonomy
Rattlesnake Venom Cathelicidin [Animal]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
Jurkat E6
RECORD: Rec_0423810 VERIFIED: YES
Provenance & Taxonomy
Crotalus durissus terrificus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans LABMIC 0125
10 μg/mL
MIC
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