Peptide Database

Peptide NameSLAY-screened peptide P1171

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC110H159N25O35S

DescriptionStandard

        DYNAFSEETKVYCIYLIHNT
    

Molecular Weight2423.65 Da

Isoelectric Point (pI)4.65

Net Charge (pH 7.0)-2.16

Net Charge (pH 7.4) -2.44

Charge Density (pH 7.0) -0.1080

GRAVY Index-0.33

Hydrophobic Moment 0.33

Boman Index0.08

Instability Index41.18

Aliphatic Index 78.00

Aromaticity 0.2000

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 990.38

LogP -7.76

H-bond Donors 35.0

H-bond Acceptors 35.0

Rotatable Bonds 76.0

Heavy Atoms 171.0

Ring Count 5.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0348180 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/