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MYP_070416
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Basic Information
Corticotropin
Antimicrobial
Cardiovascular
Delivery / Targeting ▸ Barrier transport ▸ Blood-brain barrier shuttle ▸ Blood-Brain Barrier
Delivery / Targeting ▸ Drug delivery vehicle
Hormonal / Endocrine ▸ Hormone peptide
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide precursor
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Standard
39 amino acids
C207H308N56O58S
Standard
Sequence
SYSMEHFRWGKPVGKKRRPVKVYPNGAEDESAEAFPLEF
Physicochemical Analysis
4541.07 Da
8.09
0.56
0.28
0.0143
-0.98
0.62
-0.16
53.68
40.00
0.1538
8480.00
8480.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1836.25
-15.16
63.0
61.0
145.0
322.0
12.0
39.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0252759 VERIFIED: YES
Provenance & Taxonomy
Macaca nemestrina [Animal]
POMC
9545
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Val13 Amidation; Ser31 Phosphoserine
Bio-Activity Profile
Hormone precursor Neuropeptide precursor
PMID201308 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/201308/
RECORD: Rec_0263686 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Cell-Cell Communication Drug Delivery Vehicle Blood-Brain Barrier
PaperBrainpeps: the blood-brain barrier peptide database PMID22205159 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22205159/
RECORD: Rec_0273429 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
P-copri DSMZ18205
>50 μM
MIC
PaperMining for encrypted peptide antibiotics in the human proteome.
RECORD: Rec_0285829 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Regulatory
PaperRiniker B., Sieber P., Rittel W., Zuber H.. Revised amino acid sequences for porcine and human adrenocorticotropic hormone. Nature New Biology 235, 114-115, 1972.
RECORD: Rec_0291491 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
B-eggerthi ATCC 27754
>50 μM
MIC
PaperMining for encrypted peptide antibiotics in the human proteome.
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