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MYP_070416
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Basic Information
Corticotropin
Antimicrobial
Cardiovascular
Delivery / Targeting ▸ Barrier transport ▸ Blood-brain barrier shuttle ▸ Blood-Brain Barrier
Delivery / Targeting ▸ Drug delivery vehicle
Hormonal / Endocrine ▸ Hormone peptide
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide precursor
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Standard
39 amino acids
C207H308N56O58S
Standard
Sequence
SYSMEHFRWGKPVGKKRRPVKVYPNGAEDESAEAFPLEF
Physicochemical Analysis
4541.07 Da
8.09
0.56
0.28
0.0143
-0.98
0.62
-0.16
53.68
40.00
0.1538
8480.00
8480.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1836.25
-15.16
63.0
61.0
145.0
322.0
12.0
39.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0051197 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
B-fragilis ATCC 25285
>50 μM
MIC
PaperMining for encrypted peptide antibiotics in the human proteome.
RECORD: Rec_0088714 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
K-pneumoniae ATCC 133883
>50 μM
MIC
PaperMining for encrypted peptide antibiotics in the human proteome.
RECORD: Rec_0111480 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
POMC
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Val13 Amidation; Ser31 Phosphoserine
Bio-Activity Profile
Hormone precursor Neuropeptide precursor
PMID4352834 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/4352834/
RECORD: Rec_0115084 VERIFIED: YES
Provenance & Taxonomy
Macaca nemestrina [Animal]
Corticotropin
9545
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Acetylation
13:Valine amide; 31:Phosphoserine
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator
Mammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Corticotropin (Macaca nemestrina): PMID 3229286 PMID3229286 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3229286/
RECORD: Rec_0141602 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
E-coli ATCC 11775
>50 μM
MIC
PaperMining for encrypted peptide antibiotics in the human proteome.
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