Peptide Database

Peptide NameMetalloproteinase inhibitor 1

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ Protease inhibition

Immunology ▸ Immune modulation ▸ Cytokine modulation

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Standard StatusStandard

Sequence Length184 amino acids

Chemical FormulaC918H1423N253O264S15

DescriptionStandard

        CTCVPPHPQTAFCNSDLVIRAKFVGTPEVNQTTLYQRYEIKMTKMYKGFQALGDAADIRFVYTPAMESVCGYFHRSHNRSEEFLIAGKLQDGLLHITTCSFVAPWNSLSLAQRRGFTKTYTVGCEECTVFPCLSIPCKLQSGTHCLWTDQLLQGSEKGFQSRHLACLPREPGLCTWQSLRSQIA
    

Molecular Weight20708.63 Da

Isoelectric Point (pI)8.47

Net Charge (pH 7.0)4.18

Net Charge (pH 7.4) 3.46

Charge Density (pH 7.0) 0.0227

GRAVY Index-0.17

Hydrophobic Moment 0.58

Boman Index0.03

Instability Index66.22

Aliphatic Index 73.15

Aromaticity 0.1033

Extinction Coeff. Reduced 25440.00

Extinction Coeff. Oxidized 26190.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8267.02

LogP -94.91

H-bond Donors 299.0

H-bond Acceptors 289.0

Rotatable Bonds 669.0

Heavy Atoms 1450.0

Ring Count 38.0

Amide Bonds 199.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0284695 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

Familyprotease inhibitor I35 (TIMP) family

Tax ID9606; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide1-70; 3-99; 13-124; 127-174; 132-137; 145-166

Other Mods155-Ser: Phosphoserine; by FAM20C

Bio-Activity Profile

Function

Cytokine Growth factor protease inhibitor I35 (TIMP) family