Peptide Database

Peptide NamePeptide 18

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length22 amino acids

Chemical FormulaC123H195N43O27S2

DescriptionStandard

        KRKKHRCRVYNNGLPTGLWRWC
    

Molecular Weight2772.27 Da

Isoelectric Point (pI)11.01

Net Charge (pH 7.0)6.82

Net Charge (pH 7.4) 6.53

Charge Density (pH 7.0) 0.3102

GRAVY Index-1.33

Hydrophobic Moment 0.48

Boman Index-0.45

Instability Index55.80

Aliphatic Index 48.64

Aromaticity 0.1364

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1178.19

LogP -10.11

H-bond Donors 46.0

H-bond Acceptors 37.0

Rotatable Bonds 90.0

Heavy Atoms 195.0

Ring Count 7.0

Amide Bonds 23.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0075972 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive

TargetStaphylococcus aureus ATCC 6538

Activity2.0 μM

MethodMIC