Peptide Database

Peptide NameSLAY-screened peptide P1907

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length16 amino acids

Chemical FormulaC91H131N23O23

DescriptionStandard

        SSTNHFIYYIGLLHLH
    

Molecular Weight1915.15 Da

Isoelectric Point (pI)6.78

Net Charge (pH 7.0)-0.28

Net Charge (pH 7.4) -0.64

Charge Density (pH 7.0) -0.0175

GRAVY Index0.30

Hydrophobic Moment 0.31

Boman Index0.36

Instability Index13.25

Aliphatic Index 121.88

Aromaticity 0.1875

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 730.10

LogP -4.19

H-bond Donors 26.0

H-bond Acceptors 26.0

Rotatable Bonds 58.0

Heavy Atoms 137.0

Ring Count 6.0

Amide Bonds 16.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0196223 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/