Peptide Database

Peptide NameDEFENSIN domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length95 amino acids

Chemical FormulaC446H716N130O144S7

DescriptionStandard

        MTTLTLLTAILLVPLQAQAEPLQARADKATAAQEQPGTDDQDFAISFTGDTSSGFRASGPRTLLRCSCRIRDCHLQERNYGTCTSSEIHYKFCCL
    

Molecular Weight10427.70 Da

Isoelectric Point (pI)6.03

Net Charge (pH 7.0)-1.37

Net Charge (pH 7.4) -1.79

Charge Density (pH 7.0) -0.0144

GRAVY Index-0.24

Hydrophobic Moment 0.77

Boman Index-0.04

Instability Index57.26

Aliphatic Index 75.16

Aromaticity 0.0632

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4428.58

LogP -53.89

H-bond Donors 161.0

H-bond Acceptors 152.0

Rotatable Bonds 342.0

Heavy Atoms 727.0

Ring Count 12.0

Amide Bonds 102.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0205781 VERIFIED: NO

Provenance & Taxonomy

OrganismPiliocolobus tephrosceles [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Antifungal Fungicide Non-hemolytic Non-ribosomal

MethodQualitative functional evidence