Peptide Database

Peptide NameRanatuerin-2SEa

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Immunology ▸ Adverse immune reactivity ▸ Histamine-release modulation

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Immunology ▸ Innate immune modulation ▸ Mast cell modulation

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Toxic

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC126H216N34O40S2

DescriptionStandard

        GFISTVKNLATNVAGTVIDTIKCKVTGGC
    

Molecular Weight2911.40 Da

Isoelectric Point (pI)8.86

Net Charge (pH 7.0)1.74

Net Charge (pH 7.4) 1.50

Charge Density (pH 7.0) 0.0599

GRAVY Index0.60

Hydrophobic Moment 0.51

Boman Index0.24

Instability Index-12.09

Aliphatic Index 100.69

Aromaticity 0.0345

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1201.04

LogP -15.04

H-bond Donors 44.0

H-bond Acceptors 44.0

Rotatable Bonds 97.0

Heavy Atoms 202.0

Ring Count 1.0

Amide Bonds 30.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0286473 VERIFIED: NO

Provenance & Taxonomy

OrganismLithobates sevosus [Animal]

FamilyFrog skin active peptide (FSAP); Ranatuerin subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Anti-Gram-negative Non-hemolytic

TargetMicrococcus luteus (Gram-negative)

FIRST PREV 1 ... 3 4 5

Showing 1 records · Page 5 of 5