‹ ›
MYP_070353
← PREVIOUS NEXT → BACK
Basic Information
Ranatuerin-2SEa
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Immunology ▸ Adverse immune reactivity ▸ Histamine-release modulation
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide
Immunology ▸ Innate immune modulation ▸ Mast cell modulation
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
29 amino acids
C126H216N34O40S2
Standard
Sequence
GFISTVKNLATNVAGTVIDTIKCKVTGGC
Physicochemical Analysis
2911.40 Da
8.86
1.74
1.50
0.0599
0.60
0.51
0.24
-12.09
100.69
0.0345
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1201.04
-15.04
44.0
44.0
97.0
202.0
1.0
30.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0008299 VERIFIED: YES
Provenance & Taxonomy
Lithobates sevosus [Animal]
Ranatuerin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
23-29
Bio-Activity Profile
Mast cell degranulation Histamine releasing
PaperC. Graham et al. / Peptides 27 (2006) 1313-1319. Histamine-releasing and antimicrobial peptides from the skin secretions of the dusky gopher frog, Rana sevosa Evidence URLhttps://www.uniprot.org/uniprotkb/P85057/entry
RECORD: Rec_0008934 VERIFIED: YES
Provenance & Taxonomy
Rana sevosa [Animal]
Ranatuerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli K12
PMID16386333 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16386333/
RECORD: Rec_0014785 VERIFIED: YES
Provenance & Taxonomy
Rana areolata [Animal]
Palustrin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human erythrocytes
300 μM
HC50
PMID12429503 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12429503/
RECORD: Rec_0020576 VERIFIED: YES
Provenance & Taxonomy
Rana areolata [Animal]
Ranatuerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
23-29
Bio-Activity Profile
Antimicrobial
not Staphylococcus aureus or Candida albicans
>200 μM
MIC
PaperAntimicrobial peptides and protease inhibitors in the skin secretions of the crawfish frog, Rana areolata.
RECORD: Rec_0023082 VERIFIED: YES
Provenance & Taxonomy
Lithobates sevosus [Animal]
Ranatuerin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
23-29
Bio-Activity Profile
Hemolytic Cytolytic
Erythrocytes
300.0 μM
HC50
PaperM.F. Ali et al. / Biochimica et Biophysica Acta 1601 (2002) 55-63. Antimicrobial peptides and protease inhibitors in the skin secretions of the crawfish frog, Rana areolata Evidence URLhttps://www.uniprot.org/uniprotkb/P85057/entry
1 2 3 ... 5 NEXT LAST
Showing 5 records on this page · Page 1 of 5