Peptide Database

Peptide NamehBD3-3 M1

Function Ontology

Anticancer

Antimicrobial

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC70H135N31O18S3

DescriptionStandard

        GKCSTRGRKCMRRKK
    

Molecular Weight1795.21 Da

Isoelectric Point (pI)11.58

Net Charge (pH 7.0)7.74

Net Charge (pH 7.4) 7.50

Charge Density (pH 7.0) 0.5158

GRAVY Index-1.93

Hydrophobic Moment 0.62

Boman Index-0.94

Instability Index52.91

Aliphatic Index 0.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 862.86

LogP -12.00

H-bond Donors 36.0

H-bond Acceptors 29.0

Rotatable Bonds 68.0

Heavy Atoms 122.0

Ring Count 0.0

Amide Bonds 14.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0024195 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyDefensin

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anticancer

PaperSynthetic Human β Defensin-3-C15 Peptide in Endodontics: Potential Therapeutic Agent in Streptococcus gordonii Lipoprotein-Stimulated Human Dental Pulp-Derived Cells. PMID31861863 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31861863/ PatentEP3111951B1