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MYP_070268
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Basic Information
Short α-helical peptides
Anticancer
Anticancer ▸ Antitumor
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
10 amino acids
C56H108N14O11
Standard
Sequence
GIIKKIIKKI
Physicochemical Analysis
1153.54 Da
10.48
3.76
3.55
0.3756
0.65
0.78
0.14
-33.45
195.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
429.30
0.14
15.0
15.0
45.0
81.0
0.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0096582 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Human promyelocytic leukemia HL-60
500 μM
IC50
PMID21955251 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21955251/
RECORD: Rec_0127905 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Antitumor
Human erythrocytes
250 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/21955251/ PMID21955251 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21955251/
RECORD: Rec_0136386 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PMID24246647 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24246647/
RECORD: Rec_0140618 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Alpha-helical proteins
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Anticancer Cytotoxic
HL-60
5 μM
Cytotoxicity assay
PMID24246647 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24246647/
RECORD: Rec_0190375 VERIFIED: YES
Provenance & Taxonomy
Alpha-helical proteins [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperPubMed PMID: 24246647 PMID24246647 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24246647/
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