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MYP_070268
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Basic Information
Short α-helical peptides
Anticancer
Anticancer ▸ Antitumor
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
10 amino acids
C56H108N14O11
Standard
Sequence
GIIKKIIKKI
Physicochemical Analysis
1153.54 Da
10.48
3.76
3.55
0.3756
0.65
0.78
0.14
-33.45
195.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
429.30
0.14
15.0
15.0
45.0
81.0
0.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0024302 VERIFIED: YES
Provenance & Taxonomy
Alpha-helical proteins [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
HL-60 Approx
100 %
Cytotoxicity
PaperPubMed PMID: 24246647 PMID24246647 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24246647/
RECORD: Rec_0049832 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Escherichia coli ATCC 25922
32 μM
MIC
PaperHigh Therapeutic Index alpha-Helical AMPs and Their Therapeutic Potential on Bacterial Lung and Skin Wound Infections
RECORD: Rec_0072663 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus ATCC 25923
>128 μM
MIC
PaperHigh Therapeutic Index alpha-Helical AMPs and Their Therapeutic Potential on Bacterial Lung and Skin Wound Infections
RECORD: Rec_0079145 VERIFIED: YES
Provenance & Taxonomy
Alpha-helical proteins [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
HeLa Approx
99 %
Cytotoxicity
PaperPubMed PMID: 24246647 PMID24246647 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24246647/
RECORD: Rec_0085340 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Alpha-helical proteins
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Anticancer Cytotoxic
HeLa
4 μM
Cytotoxicity assay
PMID24246647 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24246647/
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