Peptide Database

Peptide Namealpha-gliadin 4037

Function Ontology

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Immunology ▸ Immunomodulation ▸ Celiac-immunogenic

Standard StatusStandard

Sequence Length17 amino acids

Chemical FormulaC93H133N21O23S

DescriptionStandard

        PPYCTIVPFGIFGTNYR
    

Molecular Weight1945.24 Da

Isoelectric Point (pI)8.60

Net Charge (pH 7.0)0.95

Net Charge (pH 7.4) 0.87

Charge Density (pH 7.0) 0.0557

GRAVY Index0.22

Hydrophobic Moment 0.22

Boman Index0.29

Instability Index28.81

Aliphatic Index 62.94

Aromaticity 0.2353

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 683.26

LogP -4.18

H-bond Donors 25.0

H-bond Acceptors 25.0

Rotatable Bonds 53.0

Heavy Atoms 138.0

Ring Count 7.0

Amide Bonds 17.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0024679 VERIFIED: YES

Provenance & Taxonomy

OrganismTriticum aestivum [Plant]

FamilyGliadin

Tax ID4565

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Celiac-immunogenic

TargetHLA-A2+ celiac intestinal mucosa

MethodOrgan culture / CD8 T-cell assay

RECORD: Rec_0141309 VERIFIED: YES

Provenance & Taxonomy

OrganismTriticum aestivum [Plant]; Secale cereale [Plant]; Hordeum vulgare [Plant]

Tax ID4565, 4550, 4513

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Immunomodulatory