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MYP_070229
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Basic Information
MK-578
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
14 amino acids
C75H129N19O16S
Standard
Sequence
INWLKAKKVAGMIL
Physicochemical Analysis
1585.01 Da
10.30
2.76
2.55
0.1969
0.70
0.33
0.28
12.32
146.43
0.0714
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
578.56
-1.05
20.0
20.0
55.0
111.0
2.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0222449 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
42.9 μg/mL
MIC
PMID20108158 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20108158/
RECORD: Rec_0297460 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus
42.9 μg/mL
MIC
PaperInvestigating the effect of different positioning of lysine residues along the peptide chain of mastoparans for their secondary structures and biological activities.
RECORD: Rec_0309438 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Rat RBC
Hemolysis
PMID20108158 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20108158/
RECORD: Rec_0337335 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli
23.4 μg/mL
MIC
PMID20108158 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20108158/
RECORD: Rec_0346730 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa
125 μg/mL
MIC
PMID20108158 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20108158/
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