Peptide Database

Peptide NameCathelicidin-BF-15-a2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC111H165N31O16

DescriptionStandard

        VKRWKKWFRKWKKWV
    

Molecular Weight2189.70 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)7.73

Net Charge (pH 7.4) 7.51

Charge Density (pH 7.0) 0.5152

GRAVY Index-1.65

Hydrophobic Moment 0.89

Boman Index-0.50

Instability Index61.67

Aliphatic Index 38.67

Aromaticity 0.3333

Extinction Coeff. Reduced 22000.00

Extinction Coeff. Oxidized 22000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 813.80

LogP 0.94

H-bond Donors 32.0

H-bond Acceptors 24.0

Rotatable Bonds 73.0

Heavy Atoms 158.0

Ring Count 9.0

Amide Bonds 14.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0009461 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Familycathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal

TargetCandida albicans SC5314

Activity4.3 μM

MethodMIC

RECORD: Rec_0126768 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Familycathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal

TargetBacillus subtilis

Activity4.3 μM

MethodMIC

RECORD: Rec_0227879 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Familycathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hemolytic

Targethuman red blood cells

Activity10 % hemolysis at 285±16 μg/mL

MethodHemolysis

RECORD: Rec_0333836 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Familycathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal

TargetEscherichia coli ATCC 25922

Activity2.1 μM

MethodMIC

RECORD: Rec_0340138 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Familycathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal

TargetStaphylococcus aureus ATCC 2592

Activity8.5 μM

MethodMIC