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MYP_070149
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Hemostasis ▸ Anticoagulant activity
Hemostasis ▸ Antithrombotic activity
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Therapeutic / Biomedical activity ▸ Regenerative medicine ▸ Bone metabolism ▸ Osteoanabolic activity
Standard
10 amino acids
C53H84N14O15
Standard
Sequence
YQEPVLGPVR
Physicochemical Analysis
1157.32 Da
6.00
-0.24
-0.44
-0.0238
-0.42
0.40
0.01
86.04
97.00
0.1000
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
470.16
-2.89
15.0
15.0
33.0
82.0
3.0
10.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0022631 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
beta-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antithrombotic
PaperAn anticoagulant peptide from β-casein identification, structure and molecular mechanism | Liu, H. et al. | DOI: 10.1039/c8fo02235f Evidence URLhttps://www.uniprot.org/uniprotkb/P02666/entry
RECORD: Rec_0042272 VERIFIED: NO
Provenance & Taxonomy
Bos taurus [Animal]
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Immunomodulatory Cytomodulatory
RECORD: Rec_0042860 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
beta-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antioxidant Anti-inflammatory Macrophage-modulating ABTS radical scavenging ROS-reducing
Murine splenocytes
Cell proliferation assay
PaperBuffalo Milk Casein Derived Decapeptide (YQEPVLGPVR) Having Bifunctional Anti-inflammatory and Antioxidative Features Under Cellular Milieu | Kandukuri, S. et al. | DOI: 10.1007/s10989-018-9708-7 Evidence URLhttps://www.uniprot.org/uniprotkb/P02666/entry
RECORD: Rec_0159153 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913
Structure & Mods
proteolytic peptide fragment [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
PaperVariability of hydrolysis of β-, αs1-, and αs2-caseins by 10 strains of Streptococcus thermophilus and resulting bioactive peptides; Antihypertensive effect of the peptides derived from casein by an extracellular proteinase from Lactobacillus helveticus CP790 PMID22103626;8201050 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22103626/
RECORD: Rec_0198651 VERIFIED: NO
Provenance & Taxonomy
Bos taurus [Animal]
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperEvaluation of the allergenicity of goat milk, cow milk, and their lactosera in a guinea pig model PMID19233776 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19233776/
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