MYP_070135
Cytolysin
Anticancer
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Cytotoxic anticancer activity
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Cytotoxic
Antimicrobial
Antimicrobial
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Antibacterial
Antimicrobial
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Antibacterial
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Anti-Gram-negative
Antimicrobial
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Antibacterial
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Anti-Gram-positive
Toxicity / Safety
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Cytotoxicity
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Cytotoxic
Venom / Toxin
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General toxin
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Cytotoxic
Venom / Toxin
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General toxin
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Toxic
Standard
21 amino acids
C97H150N22O26S2
Standard
TTPACFTIGLGVGALFSAKFC
2104.49 Da
7.74
0.38
0.16
0.0180
1.21
0.21
0.49
31.53
83.81
0.1429
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
743.47
-6.80
28.0
29.0
63.0
147.0
4.0
20.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0008922
VERIFIED: NO
Provenance & Taxonomy
Enterococcus faecalis [Bacterium]; Bacteria [Bacterium]
1351; 2
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Paclitaxel conjugation
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0010690
VERIFIED: YES
Provenance & Taxonomy
Enterococcus faecalis [Bacterium]
Bacteriocin
1351
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Antibacterial
RECORD: Rec_0044175
VERIFIED: YES
Provenance & Taxonomy
Enterococcus faecalis [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Anti-Gram-negative
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
RECORD: Rec_0194601
VERIFIED: YES
Provenance & Taxonomy
Enterococcus faecalis [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0257550
VERIFIED: YES
Provenance & Taxonomy
Enterococcus faecalis [Bacterium]
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
AMPs: The two chains work synergistically at a ratio of 1:1. Chemical modification: CylLS contains two thioether bonds: T1-C5 and S17-C20. In addition, T2 and T7 are dehydrated. The AMINO ACID sequence of CylLL is TTPVCAVAATAAASSAACGWVGGGIFTGVTVWSLKHC. There are three thioether bonds: T1-C5, S14-C18, S34-C38. In addition, T2, T10, S15, and T30 are dehydrated. The peptide may also contain usual lanthionine stereochemistry (Tang and van der Donk, 2013 Nature Chem Biol ). Updated 1/2013; 9/2014
Bio-Activity Profile
Antimicrobial
Showing 5 records on this page · Page 1 of 2