Peptide Database

Peptide NameColicin-E2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Nuclease

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length581 amino acids

Chemical FormulaC2654H4226N814O861S9

DescriptionStandard

        MSGGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNSNSGGGSGTGGNLSAVAAPVAFGFPALSTPGAGGLAVSISAGALSAAIADIMAALKGPFKFGLWGVALYGVLPSQIAKDDPNMMSKIVTSLPADDITESPVSSLPLDKATVNVNVRVVDDVKDERQNISVVSGVPMSVPVVDAKPTERPGVFTASIPGAPVLNISVNNSTPAVQTLSPGVTNNTDKDVRPAGFTQGGNTRDAVIRFPKDSGHNAVYVSVSDVLSPDQVKQRQDEENRRQQEWDATHPVEAAERNYERARAELNQANEDVARNQERQAKAVQVYNSRKSELDAANKTLADAIAEIKQFDRFAHDPMAGGHRMWQMAGLKAQRAQTDVNNKQAAFDAAAKEKSDADAALSAAQERRKQKENKEKDAKDKLDKESKRNKPGKATGKGKPVGDKWLDDAGKDSGAPIPDRIADKLRDKEFKNFDDFRKKFWEEVSKDPDLSKQFKGSNKTNIQKGKAPFARKKDQVGGRERFELHHDKPISQDGGVYDMNNIRVTTPKRHIDIHRGK
    

Molecular Weight61601.47 Da

Isoelectric Point (pI)9.02

Net Charge (pH 7.0)6.62

Net Charge (pH 7.4) 5.64

Charge Density (pH 7.0) 0.0114

GRAVY Index-0.74

Hydrophobic Moment 0.73

Boman Index-0.11

Instability Index37.10

Aliphatic Index 62.69

Aromaticity 0.0516

Extinction Coeff. Reduced 51450.00

Extinction Coeff. Oxidized 51450.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0050911 VERIFIED: YES

Provenance & Taxonomy

OrganismEscherichia coli [Bacterium]

FamilyPyocin/Colicin

Tax ID562

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Endonuclease Hydrolase Nuclease Non-hemolytic Non-ribosomal

TargetEscherichia coli

RECORD: Rec_0208122 VERIFIED: NO

Provenance & Taxonomy

OrganismShigella sonnei [Bacterium]

FamilyColicin/Pyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Endonuclease Hydrolase Nuclease

TargetEscherichia coli