Peptide Database

Peptide NameConotoxin Vc6.2

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC141H211N37O40S6

DescriptionStandard

        GKPCHEEGQLCDPFLQNCCLGWNCVFVCI
    

Molecular Weight3256.80 Da

Isoelectric Point (pI)4.65

Net Charge (pH 7.0)-2.21

Net Charge (pH 7.4) -2.55

Charge Density (pH 7.0) -0.0761

GRAVY Index0.28

Hydrophobic Moment 0.41

Boman Index0.20

Instability Index59.10

Aliphatic Index 73.79

Aromaticity 0.1034

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1215.29

LogP -10.26

H-bond Donors 44.0

H-bond Acceptors 45.0

Rotatable Bonds 101.0

Heavy Atoms 224.0

Ring Count 7.0

Amide Bonds 32.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0151439 VERIFIED: NO

Provenance & Taxonomy

OrganismConus victoriae [Animal]

FamilyConotoxin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide4-18; 11-24; 19-28

Bio-Activity Profile

Function

Toxin

Targetmolluscan calcium currents

RECORD: Rec_0286643 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Toxic Cytotoxic