Peptide Database

Peptide NameEndolysin (EC 4.2.2.n2) (Lysis protein) (Lysozyme) (Transglycosylase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Lyase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length162 amino acids

Chemical FormulaC809H1281N225O236S6

DescriptionStandard

        MKLDKNVQRKAFLDMIAYSEGTDNGRQPTKDRGYDVIVGGKLFSDYSKHPGVYVKLNAKLTSSAAGRYQVLEKFAKHYMEQLGLPDFGPASQDKIALQLIRECKALADIDEGRIHQAIYKCRSRWASFPPPPGAGKLYNQRAESIDKMLEIFKKAGGVVTDE
    

Molecular Weight18127.58 Da

Isoelectric Point (pI)9.24

Net Charge (pH 7.0)5.76

Net Charge (pH 7.4) 5.30

Charge Density (pH 7.0) 0.0355

GRAVY Index-0.54

Hydrophobic Moment 0.71

Boman Index-0.08

Instability Index34.76

Aliphatic Index 76.54

Aromaticity 0.0926

Extinction Coeff. Reduced 17420.00

Extinction Coeff. Oxidized 17545.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7467.28

LogP -70.31

H-bond Donors 258.0

H-bond Acceptors 251.0

Rotatable Bonds 614.0

Heavy Atoms 1276.0

Ring Count 27.0

Amide Bonds 173.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0109291 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia phage isim [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Lyase Cytolytic Non-hemolytic