‹ ›
MYP_070020
← PREVIOUS NEXT → BACK
Basic Information
Big Dynorphin
Antimicrobial
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Pain modulation ▸ Pronociceptive activity
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Cell-cell communication
Standard
32 amino acids
C185H292N58O41
Standard
Sequence
YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVVT
Physicochemical Analysis
3984.66 Da
11.73
8.76
8.54
0.2736
-0.98
0.66
-0.34
59.78
66.88
0.1875
8480.00
8480.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1675.16
-12.34
62.0
50.0
135.0
284.0
8.0
34.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0300002 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiparasitic
B. vulgatus ATCC 8482
12.5 μM
MIC
PaperMining for encrypted peptide antibiotics in the human proteome.
RECORD: Rec_0313087 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Big dynorphin
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Receptor modulation
Mammalian: 2.8 hour; Yeast: 10 min; E. coli: 2 min
PaperSource-linked PubMed record(s) for Big dynorphin (Mus musculus): PMID 16292317 PMID16292317 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16292317/
RECORD: Rec_0314894 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
Opioid
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Opioid Analgesic Neuromodulator
RECORD: Rec_0319716 VERIFIED: NO
Provenance & Taxonomy
Bos taurus [Animal]
Opioid
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Opioid Analgesic Neuromodulator
RECORD: Rec_0334185 VERIFIED: NO
Provenance & Taxonomy
Cavia porcellus [Animal]
Opioid
10141
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Opioid Analgesic Neuromodulator
FIRST PREV 1 ... 3 4 5 6 NEXT LAST
Showing 5 records on this page · Page 5 of 6