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MYP_070020
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Basic Information
Big Dynorphin
Antimicrobial
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Pain modulation ▸ Pronociceptive activity
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Cell-cell communication
Standard
32 amino acids
C185H292N58O41
Standard
Sequence
YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVVT
Physicochemical Analysis
3984.66 Da
11.73
8.76
8.54
0.2736
-0.98
0.66
-0.34
59.78
66.88
0.1875
8480.00
8480.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1675.16
-12.34
62.0
50.0
135.0
284.0
8.0
34.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0090061 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Big dynorphin
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Analgesic Pronociceptive Neuropeptide Neuromodulator Receptor modulation
Mammalian: 2.8 hour; Yeast: 10 min; E. coli: 2 min
PaperSource-linked PubMed record(s) for Big dynorphin (Rattus norvegicus): PMID 3858883 PMID3858883 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3858883/
RECORD: Rec_0124307 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiparasitic
A. muciniphila ATCC BAA-835
50 μM
MIC
PaperMining for encrypted peptide antibiotics in the human proteome.
RECORD: Rec_0127541 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiparasitic
Pseudomonas aeruginosa PA01
25 μM
MIC
PaperMining for encrypted peptide antibiotics in the human proteome.
RECORD: Rec_0141758 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiparasitic
P-distasonis ATCC 8503
>50 μM
MIC
PaperMining for encrypted peptide antibiotics in the human proteome.
RECORD: Rec_0142347 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiparasitic
B-uniformis ATCC 8492
>50 μM
MIC
PaperMining for encrypted peptide antibiotics in the human proteome.
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