Peptide Database

Peptide NameBeta-defensin 12

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length51 amino acids

Chemical FormulaC248H397N75O72S7

DescriptionStandard

        GLEYSQSFPGGEIAVCETCRLGRGKCRRTCIESEKIAGWCKLNFFCCRERI
    

Molecular Weight5805.72 Da

Isoelectric Point (pI)8.58

Net Charge (pH 7.0)2.70

Net Charge (pH 7.4) 2.38

Charge Density (pH 7.0) 0.0530

GRAVY Index-0.27

Hydrophobic Moment 0.56

Boman Index-0.11

Instability Index50.90

Aliphatic Index 63.14

Aromaticity 0.0980

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2406.14

LogP -25.10

H-bond Donors 94.0

H-bond Acceptors 82.0

Rotatable Bonds 196.0

Heavy Atoms 402.0

Ring Count 7.0

Amide Bonds 52.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0071204 VERIFIED: NO

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyDefensin

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

RECORD: Rec_0279935 VERIFIED: YES