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MYP_069980
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Basic Information
natriuretic peptide PtNP-a
Antimicrobial
Cardiovascular
Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide
Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Hormonal / Endocrine ▸ Hormone peptide
Membrane / Ion-channel modulation ▸ Ion channel modulation
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Standard
40 amino acids
C167H278N56O56S3
Standard
Sequence
SGSKIGNGCFGLPLDRISNTSGMGCRNPIQNRPKSTPGGS
Physicochemical Analysis
4062.53 Da
10.10
3.44
3.20
0.0860
-0.68
0.48
-0.09
12.82
48.75
0.0250
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1815.39
-29.53
64.0
63.0
133.0
282.0
5.0
44.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0002280 VERIFIED: YES
Provenance & Taxonomy
Pseudonaja textilis [Animal]
natriuretic peptide PtNP
8673
Structure & Mods
linear peptide with reported disulfide constraint [Linear]
canonical L-amino-acid peptide [L]
9-25
Bio-Activity Profile
Hormone Endocrine Vasoactive Vasodilator Cardiovascular Metabolic regulation Physiological regulation Enzyme modulation Ion channel modulation Receptor modulation ACE inhibitory
Mammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour
PaperCloning and characterisation of natriuretic peptides from the venom glands of Australian elapids PMID16908092 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16908092/
RECORD: Rec_0226766 VERIFIED: YES
Provenance & Taxonomy
Pseudonaja textilis [Animal]
natriuretic peptide PtNP
8673
Structure & Mods
linear peptide with reported disulfide constraint [Linear]
canonical L-amino-acid peptide [L]
9-25
Bio-Activity Profile
Hormone Endocrine Vasoactive Vasodilator Cardiovascular Metabolic regulation Physiological regulation Enzyme modulation Ion channel modulation Receptor modulation ACE inhibitory
converting enzyme
Mammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour
PaperCloning and characterisation of natriuretic peptides from the venom glands of Australian elapids PMID16908092 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16908092/
RECORD: Rec_0423343 VERIFIED: NO
Provenance & Taxonomy
Pseudonaja textilis [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
9-25
Bio-Activity Profile
Antimicrobial