Peptide Database

Peptide NameInsulin A chain

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC99H151N25O38S4

DescriptionStandard

        GIVEQCCENTCSLYELENYCN
    

Molecular Weight2427.66 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-4.27

Net Charge (pH 7.4) -4.54

Charge Density (pH 7.0) -0.2033

GRAVY Index-0.30

Hydrophobic Moment 0.35

Boman Index0.02

Instability Index-0.61

Aliphatic Index 69.52

Aromaticity 0.0952

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1047.80

LogP -12.14

H-bond Donors 38.0

H-bond Acceptors 38.0

Rotatable Bonds 79.0

Heavy Atoms 166.0

Ring Count 2.0

Amide Bonds 24.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0295696 VERIFIED: YES

Provenance & Taxonomy

OrganismPtyas dhumnades [Animal]

FamilyInsulin

Tax ID8587

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide6-11

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation

Half-LifeMammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour