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MYP_069889
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Basic Information
Trichogin GA IV Ome
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
not Standard
10 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
XGLXGGLXGI
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0032009 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
C8
Methyl ester
X=AIB (Aminoisobutyric acid)
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID25306964 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25306964/
RECORD: Rec_0057916 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Octanoylation
Lol (leucinol)
Aib (α-aminoisobutyric acid)
Bio-Activity Profile
Antimicrobial Antifungal Antibacterial
Human erythrocytes
15 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/19399781/ PMID19399781 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19399781/
RECORD: Rec_0206512 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
mixed L/D or residue-modified peptide [Mixed]
Acetylated by n-octanoyl
Lol (leucinol)
Aib (α-aminoisobutyric acid)
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Toxic Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0358265 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
C8
Methyl ester
X=AIB (Aminoisobutyric acid)
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID25306964 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25306964/
RECORD: Rec_0391294 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
C8
Methyl ester
X=AIB (Aminoisobutyric acid)
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PMID25306964 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25306964/