Peptide Database

Peptide NameCholecystokinin-39

Function Ontology

Gastrointestinal bioactivity

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological modulation

Standard StatusStandard

Sequence Length39 amino acids

Chemical FormulaC201H315N61O59S3

DescriptionStandard

        YIQQARKAPSGRMSVIKNLQNLDPSHRISDRDYMGWMDF
    

Molecular Weight4626.22 Da

Isoelectric Point (pI)9.52

Net Charge (pH 7.0)1.85

Net Charge (pH 7.4) 1.59

Charge Density (pH 7.0) 0.0474

GRAVY Index-0.87

Hydrophobic Moment 0.53

Boman Index-0.20

Instability Index63.58

Aliphatic Index 62.56

Aromaticity 0.1026

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1981.68

LogP -20.16

H-bond Donors 69.0

H-bond Acceptors 65.0

Rotatable Bonds 154.0

Heavy Atoms 324.0

Ring Count 8.0

Amide Bonds 43.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0143788 VERIFIED: YES

Provenance & Taxonomy

OrganismCanis lupus familiaris [Animal]

FamilyCholecystokinin

Tax ID9615

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

C-TermAmidation

Other Mods33:Sulfotyrosine

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Myotropic Receptor modulation

Half-LifeMammalian: 2.8 hour; Yeast: 10 min; E. coli: 2 min

RECORD: Rec_0154025 VERIFIED: YES

Provenance & Taxonomy

OrganismCanis familiaris [Animal]

FamilyGastrin/cholecystokinin

Tax ID9615

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Other ModsTyr33 Sulfotyrosine

Bio-Activity Profile

Function

Hormone Gastrointestinal Neuropeptide

RECORD: Rec_0306167 VERIFIED: YES

Provenance & Taxonomy

OrganismCanis lupus familiaris [Animal]

FamilyCholecystokinin

Tax ID9615

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

C-TermAmidation

Other Mods33:Sulfotyrosine

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Myotropic Receptor modulation

TargetCCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion

Half-LifeMammalian: 2.8 hour; Yeast: 10 min; E. coli: 2 min