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MYP_069859
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Basic Information
Maximin 3/H9 2
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Antiviral
Antiviral ▸ Anti-HIV ▸ Anti-HIV-1
Reproductive biology ▸ Contraceptive activity ▸ Spermicidal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
20 amino acids
C93H167N23O23
Standard
Sequence
ILGPVLGLVSNALGGLIKKI
Physicochemical Analysis
1975.46 Da
10.00
1.76
1.55
0.0879
1.37
0.54
0.52
26.44
190.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
722.79
-3.53
24.0
25.0
67.0
139.0
1.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0006553 VERIFIED: NO
Provenance & Taxonomy
Bombina maxima [Animal]; Bombina microdeladigitora [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
RECORD: Rec_0141737 VERIFIED: YES
Provenance & Taxonomy
Bombina maxima [Animal]
Maximin H
161274
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anticancer Antiviral Anti-HIV-1 Spermicidal
PaperR. Lai et al. / Peptides 23 (2002) 427-435. Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima PMID11835991 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11835991/
RECORD: Rec_0182624 VERIFIED: YES
Provenance & Taxonomy
Bombina maxima [Animal]
Maximin H
161274
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
PaperR. Liu et al. / Journal of Proteome Research 10 (2011) 1806-1815. There are abundant antimicrobial peptides in brains of two kinds of Bombina toads PMID21338048 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21338048/
RECORD: Rec_0193092 VERIFIED: YES
Provenance & Taxonomy
Bombina maxima [Animal]
Maximin
161274
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Strong hemolytic activity
Hemolysis
PaperMaximin-H9 Evidence URLhttps://www.uniprot.org/uniprotkb/Q58T80/entry
RECORD: Rec_0268170 VERIFIED: YES
Provenance & Taxonomy
Bombina maxima [Animal]
Bombinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
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