MYP_069847
Microcin B
Antimicrobial
Antimicrobial
▸
Antibacterial
Antimicrobial
▸
Antibacterial
▸
Anti-Gram-negative
Standard
42 amino acids
C112H177N47O52S4
Standard
VGIGGGGGGGGGGSCGGQGGGCGGCSNGCSGGNGGSGGSGSH
3142.15 Da
6.68
-0.22
-0.54
-0.0052
-0.24
0.22
0.29
51.31
16.19
0.0000
0.00
250.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
1535.75
-38.95
57.0
57.0
105.0
215.0
1.0
44.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0042711
VERIFIED: YES
Provenance & Taxonomy
Escherichia coli [Bacterium]; Bacteria [Bacterium]
Microcin
562; 2
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0171342
VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial
Antimicrobial
Anti-Gram-negative
RECORD: Rec_0346957
VERIFIED: YES
Provenance & Taxonomy
Escherichia coli [Bacterium]
Microcin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
post-translational modifications of GSC, GCS, and GCS triplets led to fused heterocycles in three locations. MOA:bacteria:E. coli: These fused heterocycles could contribute to the binding to DNA gyrase-DNA complex, the likely target of MccB. Without fused heterocycle at site B, the peptide is inactive
Bio-Activity Profile
Antimicrobial
Escherichia coli BL21 DE3
0.06 μM
MIC