Peptide Database

Peptide NameBrevinin-1PLb

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length70 amino acids

Chemical FormulaC362H584N92O105S6

DescriptionStandard

        MFTTKKSMLLLFFLGTINLSLCEEERNAEEERRDEPDEMNVEVEKRFLPLIAGLAANFLPKIFCAITKKC
    

Molecular Weight8097.45 Da

Isoelectric Point (pI)5.10

Net Charge (pH 7.0)-2.50

Net Charge (pH 7.4) -2.79

Charge Density (pH 7.0) -0.0358

GRAVY Index-0.06

Hydrophobic Moment 0.58

Boman Index0.01

Instability Index45.69

Aliphatic Index 93.43

Aromaticity 0.0857

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3189.91

LogP -23.37

H-bond Donors 111.0

H-bond Acceptors 109.0

Rotatable Bonds 278.0

Heavy Atoms 565.0

Ring Count 9.0

Amide Bonds 73.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0011407 VERIFIED: YES

Provenance & Taxonomy

OrganismLithobates palustris [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetStaphylococcus aureus

RECORD: Rec_0195016 VERIFIED: YES