Peptide Database

Peptide NameBottromycin D

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Staphylococcus aureus

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length46 amino acids

Chemical FormulaC216H318N52O82S4

DescriptionStandard

        MGPAVVFDCMTADFLNDDPNNAELSSLEMEELESWGAWSDDTDQSV
    

Molecular Weight5083.39 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-12.49

Net Charge (pH 7.4) -12.73

Charge Density (pH 7.0) -0.2715

GRAVY Index-0.40

Hydrophobic Moment 0.39

Boman Index0.07

Instability Index37.27

Aliphatic Index 61.52

Aromaticity 0.0870

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2148.39

LogP -23.89

H-bond Donors 71.0

H-bond Acceptors 74.0

Rotatable Bonds 163.0

Heavy Atoms 354.0

Ring Count 8.0

Amide Bonds 49.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0275193 VERIFIED: YES

Provenance & Taxonomy

OrganismStreptomyces sp [Bacterium]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-MRSA Anti-Gram-positive Non-hemolytic

TargetStaphylococcus aureus