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MYP_069654
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Basic Information
Odorranain-F-OA1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
29 amino acids
C132H226N38O40S4
Standard
Sequence
GFMDTAKNVAKNMAGNLLDNLKCKITKAC
Physicochemical Analysis
3113.70 Da
9.24
2.74
2.50
0.0944
-0.13
0.61
-0.01
15.10
77.59
0.0345
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1295.64
-14.38
45.0
47.0
110.0
214.0
1.0
32.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0321004 VERIFIED: YES
Provenance & Taxonomy
Odorrana andersonii [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
23-29
Bio-Activity Profile
Antimicrobial Antifungal
Staphylococcus aureus
2.5 μg/mL
MIC
PaperExtremely Abundant Antimicrobial Peptides Existed in the Skins of Nine Kinds of Chinese Odorous Frogs PMID22029824 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22029824/
RECORD: Rec_0327797 VERIFIED: YES
Provenance & Taxonomy
Odorrana andersonii [Animal]
Brevinin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans ATCC 2002
2.5 μg/mL
MIC
PMID22029824 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22029824/
RECORD: Rec_0365550 VERIFIED: YES
Provenance & Taxonomy
Odorrana andersonii [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0388783 VERIFIED: YES
Provenance & Taxonomy
Odorrana andersonii [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
23-29
Bio-Activity Profile
Antimicrobial Antifungal
Escherichia coli
5.0 μg/mL
MIC
PaperExtremely Abundant Antimicrobial Peptides Existed in the Skins of Nine Kinds of Chinese Odorous Frogs PMID22029824 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22029824/
RECORD: Rec_0420868 VERIFIED: YES
Provenance & Taxonomy
Odorrana andersonii [Animal]
Odorranain
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
23-29
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
1.61 μM
MIC
PaperX. Yang et al. / Journal of Proteome Research 11 (2012) 306-319. Extremely Abundant Antimicrobial Peptides Existed in the Skins of Nine Kinds of Chinese Odorous Frogs PMID22029824 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22029824/
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