Peptide Database

Peptide NameC-X-C motif chemokine 6 (Granulocyte chemotactic protein 2) (GCP-2) (Small-inducible cytokine B6)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Immunology ▸ Immune cell migration ▸ Chemotactic peptide

Immunology ▸ Immune modulation ▸ Cytokine modulation

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length112 amino acids

Chemical FormulaC509H877N145O148S6

DescriptionStandard

        MRLLSSRAARVSGPSGSLCALLALLLLTPPGPLASAGPVAAVVRELRCVCLTTTPGIHPKTVSDLQVIAAGPQCSKVEVIATLKNGREVCLDPEAPLIKKIVQKILDSGKNN
    

Molecular Weight11588.68 Da

Isoelectric Point (pI)9.40

Net Charge (pH 7.0)5.55

Net Charge (pH 7.4) 5.19

Charge Density (pH 7.0) 0.0495

GRAVY Index0.36

Hydrophobic Moment 0.76

Boman Index0.13

Instability Index25.75

Aliphatic Index 119.29

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 250.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4610.83

LogP -47.79

H-bond Donors 162.0

H-bond Acceptors 161.0

Rotatable Bonds 380.0

Heavy Atoms 808.0

Ring Count 11.0

Amide Bonds 117.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0063452 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyIntercrine alpha (chemokine CxC)

Tax ID9913

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Cytokine Chemotactic Non-hemolytic

TargetGram Negative Bacteria and Gram Positive Bacteria