Peptide Database

Peptide NameBactericidal permeability-increasing protein

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length507 amino acids

Chemical FormulaC2592H4006N642O743S17

DescriptionStandard

        MCTKIIPVLWGCFLLWNLYISSSYTIYPGIKARITQRALDYGVQAGMEMIEQMLKQKNLPDLSGSESLEFLKVDYVNYNFSNIKINAFSFPNTSLAFVPGVGIKALTNHGTANISTDWEFKSPIFQDTGGADLFLSGVYFTGIIILTRNDFGHPILKLQDCYAQVSHAHVSFSGELSVLYNSFAEPMEKPILKNLNEMLCPIIANEVEALNANLSTLEVLTRIDNYTLLDYSLISSPEITENYLDLNLKGVFYPLENLVDPYFSPVPFVLPERSNSMLYIGIAEYFFKSASFAYFTAGAFNVTLSTKEISNHFVQNSQGLGNVLSRIAEIYILSQPFMVRIMATEPPVINLQPGNFTLDIPASIMMLTQTKNSTVETIVSMDFVASTSVGLVILGQRLVCSLSLNRFRLALPESNRSNIEVLRFENILSSILHFGVLPLANAKLQQGFPLPNPHKISFVNSDIEVLEGFLLISTDLKYETSSKQHPSFHGWEGLNLISGWWRGKSAP
    

Molecular Weight56594.49 Da

Isoelectric Point (pI)5.37

Net Charge (pH 7.0)-10.71

Net Charge (pH 7.4) -11.57

Charge Density (pH 7.0) -0.0211

GRAVY Index0.16

Hydrophobic Moment 0.68

Boman Index0.19

Instability Index36.84

Aliphatic Index 103.06

Aromaticity 0.1124

Extinction Coeff. Reduced 61310.00

Extinction Coeff. Oxidized 61560.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0420217 VERIFIED: NO

Provenance & Taxonomy

OrganismCallithrix jacchus [Animal]

FamilyBPI/LBP

Tax ID9483

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic Non-ribosomal

TargetGram-negative bacteria

MethodQualitative functional evidence