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MYP_069604
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
4 amino acids
C25H40N6O7
Standard
Sequence
YNKL
Physicochemical Analysis
536.62 Da
8.59
0.76
0.55
0.1895
-1.23
0.65
-0.24
45.48
97.50
0.2500
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
239.96
-1.15
8.0
8.0
17.0
38.0
1.0
4.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0239586 VERIFIED: YES
Provenance & Taxonomy
Undaria pinnatifida [Protist]
ACE inhibitory peptide
74381
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory Antihypertensive Enzyme-inhibitory
Angiotensin-converting enzyme
21 μM
IC50
PaperIdentification of an antihypertensive peptide from peptic digest of wakame (Undaria pinnatifida) | Review on the angiotensin-I-converting enzyme (ACE) inhibitor peptides from marine proteins | Vegetable foods: a cheap source of proteins and peptides with antihypertensive, antioxidant, and other less occurrence bioactivities | Isolation and characterization of peptides with antihypertensive activity in foodstuffs
RECORD: Rec_0256024 VERIFIED: YES
Provenance & Taxonomy
Undaria pinnatifida [Plant]
Angiotensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory
Angiotensin-I converting enzyme
21 μM
IC50
RECORD: Rec_0298776 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
21 μM
IC50
PaperIntegration of QSAR modelling and QM/MM analysis to investigate functional food peptides with antihypertensive activity
RECORD: Rec_0311025 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antihypertensive
PaperAHTPDB: a comprehensive platform for analysis and presentation of antihypertensive peptides PMID25392419 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25392419/
RECORD: Rec_0338419 VERIFIED: NO
Provenance & Taxonomy
Undaria pinnatifida [Protist]
ACE-inhibitory peptide
74381
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
Spontaneously hypertensive rat (SHR)
50 mmHg
SBP decrease
PaperReview on the angiotensin-I-converting enzyme (ACE) inhibitor peptides from marine proteins. PMID23271625 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23271625/
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