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MYP_069586
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Basic Information
Lactoferrampin
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Antimicrobial ▸ Antifungal
Binding / Molecular interaction ▸ Binding activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
17 amino acids
C93H154N28O24
Standard
Sequence
WKLLSKAQEKFGKNKSR
Physicochemical Analysis
2048.39 Da
10.58
4.76
4.55
0.2799
-1.48
0.58
-0.44
36.01
51.76
0.1176
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
900.65
-8.24
32.0
29.0
75.0
145.0
3.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0184273 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D or modified amino-acid peptide [Mixed]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PMID30048118 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30048118/
RECORD: Rec_0239388 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Transferrin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-negative
Candida albicans SC5314
25 μM
MIC
PMID30658284 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30658284/
RECORD: Rec_0269623 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Transferrin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-negative
Pseudomonas aeruginosa
9.5 μM
MIC
PMID30658284 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30658284/
RECORD: Rec_0304461 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Streptococcus mutans
>100 μM
MIC
PaperLactoferrampin: a novel antimicrobial peptide in the N1-domain of bovine lactoferrin.
RECORD: Rec_0316532 VERIFIED: NO
Provenance & Taxonomy
Bos taurus [Animal]
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus and, Escherichia coli and fungus, Candida albicans
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