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MYP_069586
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Basic Information
Lactoferrampin
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Antimicrobial ▸ Antifungal
Binding / Molecular interaction ▸ Binding activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
17 amino acids
C93H154N28O24
Standard
Sequence
WKLLSKAQEKFGKNKSR
Physicochemical Analysis
2048.39 Da
10.58
4.76
4.55
0.2799
-1.48
0.58
-0.44
36.01
51.76
0.1176
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
900.65
-8.24
32.0
29.0
75.0
145.0
3.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0098230 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Lactoferrampin
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative Antifungal
Escherichia coli; Candida albicans
MIC
PaperA one-enzyme strategy to release an antimicrobial peptide from the LFampin-domain of bovine lactoferrin | Bolscher, JGM. et al. | DOI: 10.1016/j.peptides.2005.06.012 Evidence URLhttps://www.uniprot.org/uniprotkb/P24627/entry
RECORD: Rec_0102717 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D or modified amino-acid peptide [Mixed]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID30048118 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30048118/
RECORD: Rec_0153560 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 35.3%, E 0.0%, T 35.3%, C 29.4% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
PaperBaAMPs: the database of biofilm-active antimicrobial peptides PMID25760404 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25760404/
RECORD: Rec_0165408 VERIFIED: NO
Provenance & Taxonomy
Bos taurus [Animal]
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperPatent KR 20200056194 A Evidence URLhttps://patents.google.com/patent/KR20200056194A/en PatentKR 20200056194 A
RECORD: Rec_0180354 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Lactoferrin-derived
9606;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiofilm Antibacterial
Pseudomonas aeruginosa
1, 5, 25 μM
Crystal violet assay
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