Peptide Database

Peptide NameLongicornsin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length46 amino acids

Chemical FormulaC227H352N68O55S11

DescriptionStandard

        FGCGQGMIFMCQRRCMRLYPGSTGFCRGFRCMCDTHIPLRPPFMVG
    

Molecular Weight5266.36 Da

Isoelectric Point (pI)9.25

Net Charge (pH 7.0)4.79

Net Charge (pH 7.4) 4.44

Charge Density (pH 7.0) 0.1041

GRAVY Index0.13

Hydrophobic Moment 0.73

Boman Index0.05

Instability Index56.87

Aliphatic Index 40.22

Aromaticity 0.1304

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1942.14

LogP -17.69

H-bond Donors 75.0

H-bond Acceptors 72.0

Rotatable Bonds 166.0

Heavy Atoms 361.0

Ring Count 11.0

Amide Bonds 47.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0382075 VERIFIED: YES

Provenance & Taxonomy

OrganismHaemaphysalis longicornis [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus aureus ATCC 2592

Activity0.8 μg/mL

MethodMIC

RECORD: Rec_0389496 VERIFIED: YES