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MYP_069561
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Basic Information
Longicornsin
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
46 amino acids
C227H352N68O55S11
Standard
Sequence
FGCGQGMIFMCQRRCMRLYPGSTGFCRGFRCMCDTHIPLRPPFMVG
Physicochemical Analysis
5266.36 Da
9.25
4.79
4.44
0.1041
0.13
0.73
0.05
56.87
40.22
0.1304
1490.00
1865.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1942.14
-17.69
75.0
72.0
166.0
361.0
11.0
47.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0086002 VERIFIED: YES
Provenance & Taxonomy
Haemaphysalis longicornis [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli 23A
6.4 μg/mL
MIC
PMID20027626 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20027626/
RECORD: Rec_0215752 VERIFIED: YES
Provenance & Taxonomy
Haemaphysalis longicornis [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus 6A
0.8 μg/mL
MIC
PMID20027626 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20027626/
RECORD: Rec_0359168 VERIFIED: YES
Provenance & Taxonomy
Haemaphysalis longicornis [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Very low hemolytic activity against rabbit erythrocytes.
Hemolysis
PMID20027626 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20027626/
RECORD: Rec_0363215 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 17.4%, E 17.4%, T 26.1%, C 39.1% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Antifungal
PaperCAMP: Collection of sequences and structures of antimicrobial peptides PMID24265220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24265220/
RECORD: Rec_0372394 VERIFIED: YES
Provenance & Taxonomy
Haemaphysalis longicornis [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
3.2 μg/mL
MIC
PMID20027626 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20027626/
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