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MYP_069482
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Basic Information
Bac5 281
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
17 amino acids
C114H174N40O19
Standard
Sequence
RWRRPIRRRPIRPPFYW
Physicochemical Analysis
2408.86 Da
12.00
6.76
6.55
0.3976
-1.72
0.58
-0.67
213.91
45.88
0.2353
12490.00
12490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
978.87
-4.25
38.0
26.0
69.0
173.0
10.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0145407 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli EURL-VTEC A07 EPEC:O111
2 μM
MIC
PMID31692278 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31692278/
RECORD: Rec_0173412 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperProline-Rich Peptides with Improved Antimicrobial Activity against E. coli, K. pneumoniae, and A. baumannii. ChemMedChem. 2019 Dec 17;14(24):2025-2033. doi: 10.1002/cmdc.201900465. PMID: 31692278. PMID31692278 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31692278/
RECORD: Rec_0249231 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli C679-12 EAEC:0104
2 μM
MIC
PMID31692278 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31692278/
RECORD: Rec_0313589 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PaperProline-Rich Peptides with Improved Antimicrobial Activity against E. coli, K. pneumoniae, and A. baumannii. ChemMedChem. 2019 Dec 17;14(24):2025-2033. doi: 10.1002/cmdc.201900465. PMID: 31692278. PMID31692278 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31692278/
RECORD: Rec_0325657 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Klebsiella pneumoniae ATCC 700603
64 μM
MIC
PMID31692278 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31692278/
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