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MYP_069378
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Basic Information
Met-enkephalin-Arg-Phe
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid
Neurological / Signaling ▸ Analgesic/opioid activity ▸ opioid neuropeptide precursor family
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide signaling
Neurological / Signaling ▸ Neuropeptide activity ▸ opioid neuropeptide precursor family
Neurological / Signaling ▸ Pain modulation ▸ Pronociceptive activity
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity
Standard
7 amino acids
C42H56N10O9S
Standard
Sequence
YGGFMRF
Physicochemical Analysis
877.02 Da
8.75
0.76
0.55
0.1084
0.13
0.52
0.24
3.30
0.00
0.4286
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
320.05
-0.98
12.0
11.0
26.0
62.0
3.0
6.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0293813 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Opioid
opioid receptor
PaperMcDonald J., Lambert D. G.. Opioid mechanisms and opioid drugs. Anaesthesia and Intensive Care Medicine, 2007, 9:1, 33-37.
RECORD: Rec_0364242 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Opioid
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Opioid Analgesic Neuromodulator
PMID20298575 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20298575/
RECORD: Rec_0377296 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Opioid
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Opioid Analgesic Neuromodulator
PMID20298575 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20298575/
RECORD: Rec_0388692 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Enkephalin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Opioid
Rabbit plasma: 45 s in vivo; 1 min 8 s in vitro
PMID6343745 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/6343745/
RECORD: Rec_0398537 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Cell-Cell Communication
PaperNeuroPedia: neuropeptide database and spectral library PMID21821666 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21821666/
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