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MYP_069378
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Basic Information
Met-enkephalin-Arg-Phe
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid
Neurological / Signaling ▸ Analgesic/opioid activity ▸ opioid neuropeptide precursor family
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide signaling
Neurological / Signaling ▸ Neuropeptide activity ▸ opioid neuropeptide precursor family
Neurological / Signaling ▸ Pain modulation ▸ Pronociceptive activity
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity
Standard
7 amino acids
C42H56N10O9S
Standard
Sequence
YGGFMRF
Physicochemical Analysis
877.02 Da
8.75
0.76
0.55
0.1084
0.13
0.52
0.24
3.30
0.00
0.4286
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
320.05
-0.98
12.0
11.0
26.0
62.0
3.0
6.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0056726 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
opioid neuropeptide precursor family
9606; 0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide opioid neuropeptide precursor family Growth factor signaling Hormone Neuropeptide signaling
PaperPDB 2LWC structural record; NMR; chain A; residues 1-5
RECORD: Rec_0067980 VERIFIED: NO
Provenance & Taxonomy
Rattus norvegicus [Animal]
Met-enkephalin-Arg-Phe
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Analgesic Pronociceptive Neuropeptide Neuromodulator Growth regulation Development regulation Receptor modulation
Mammalian: 2.8 hour; Yeast: 10 min; E. coli: 2 min
RECORD: Rec_0102368 VERIFIED: YES
Provenance & Taxonomy
Coturnix japonica [Animal]
MERF
93934
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide Neuromodulator
Mammalian: 2.8 hour; Yeast: 10 min; E. coli: 2 min
PaperSource-linked PubMed record(s) for MERF (Coturnix japonica): PMID 20298575 PMID20298575 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20298575/
RECORD: Rec_0148208 VERIFIED: YES
Provenance & Taxonomy
Coturnix coturnix japonica [Animal]
Opioid
93934
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Opioid Analgesic Neuromodulator
PMID20298575 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20298575/
RECORD: Rec_0191562 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Met-enkephalin-Arg-Phe
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Analgesic Pronociceptive Hormone Endocrine Neuropeptide Neuromodulator Growth regulation Development regulation Receptor modulation
Mammalian: 2.8 hour; Yeast: 10 min; E. coli: 2 min
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